(R)-5-(苄氧基)-2-(苄氧基羰基氨基)-5-羰基戊酸合成路线 (共 5 条)
反应条件
potassium hydrogencarbonate
参考文献
Journal of the Chemical Society, , p. 3239,3243
反应条件
1: aqueous HI 2: aqueous KHCO3 View Scheme
参考文献
Journal of the Chemical Society, , p. 3239,3243
反应条件
1: aqueous HI 2: aqueous KHCO3 View Scheme
参考文献
Journal of the Chemical Society, , p. 3239,3243
反应条件
1: 1.) triethylamine, ethyl chloroformate / 1.) THF, -10 deg C, 15 min, 2.)a) THF, -10 deg C, 1 h, b) RT, 3 h 2: H2, H2O / 10percent Pd/activated charcoal / methanol / 2 h / 760 Torr / Ambient temperature 3: aq. NaOH / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38
反应条件
1: 1.) triethylamine, ethyl chloroformate / 1.) THF, -10 deg C, 15 min, 2.)a) THF, -10 deg C, 1 h, b) RT, 3 h 2: H2, H2O / 10percent Pd/activated charcoal / methanol / 2 h / 760 Torr / Ambient temperature 3: aq. NaOH / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Makovec, Francesco; Peris, Walter; Revel, Laura; Giovanetti, Roberto; Mennuni, Laura; Rovati, Lucio C.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 28 - 38