2-氨基-5-溴吡嗪合成路线

PFIZER INC.; CORBETT, Jeffrey Wayne; GUZMAN-PEREZ, Angel; PFEFFERKORN, Jeffrey Allen; TU, Meihua Mike
Patent: WO2010/103438 A1, 2010 ;
Location in patent: Page/Page column 42 ;

59489-71-32-氨基-5-溴吡嗪+

108-24-7乙酸酐

174680-67-2

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; TREU, Matthias; KARNER, Thomas; REISER, Ulrich
Patent: WO2010/12747 A1, 2010 ;
Location in patent: Page/Page column 18 ;

59489-71-32-氨基-5-溴吡嗪+

5720-07-04-甲氧基苯硼酸

119738-50-05-(4-甲氧基苯基)-2-氨基吡嗪

参考文献

Chou, Chun-Ming; Tung, Yu-Wen; Lin, Meng-I; Chan, Diana; Phakhodee, Wong; Isobe, Minoru
Heterocycles, 2012 , vol. 86, # 2 p. 1323 - 1339

59489-71-32-氨基-5-溴吡嗪+

6165-69-1

710323-21-0

参考文献

SUGEN, INC.
Patent: WO2005/113548 A1, 2005 ;
Location in patent: Page/Page column 48 ;
WO 2005/113548 A1

59489-71-32-氨基-5-溴吡嗪+

151-50-8

89323-09-1+

40155-43-9

参考文献

Ellingson; Henry
Journal of the American Chemical Society, 1949 , vol. 71, p. 2798

59489-71-32-氨基-5-溴吡嗪+

73183-34-3

947249-41-4

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Burger, Matthew T.; Knapp, Mark; Wagman, Allan; Ni, Zhi-Jie; Hendrickson, Thomas; Atallah, Gordana; Zhang, Yanchen; Frazier, Kelly; Verhagen, Joelle; Pfister, Keith; Ng, Simon; Smith, Aaron; Bartulis, Sarah; Merrit, Hanne; Weismann, Marion; Xin, Xiaohua; Haznedar, Joshua; Voliva, Charles F.; Iwanowicz, Ed; Pecchi, Sabina
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