(4Z)-4-壬烯基-1-醇合成路线 （共 44 条）
反应条件
1: 80 percent / PBr3, pyridine / diethyl ether / 1 h / 5 °C
3: pyridine
View Scheme
参考文献
Tolstikov, G. A.; Odinokov, V. N.; Galeeva, R. I.; Bakeeva, R. S.; Akhunova, V. R.
Chemistry of Natural Compounds, 1982 , vol. 18, # 2 p. 219 - 224
Khimiya Prirodnykh Soedinenii, 1982 , vol. 18, # 2 p. 239 - 245
反应条件
1: tetrahydrofuran / 0.33 h / 20 °C
2: LiBr / tetrahydrofuran; hexamethylphosphoric acid triamide / 2 h / Heating
3: 81 percent / dimethylformamide / 4 h / 110 °C
4: 66 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 - -50 °C
5: 84 percent / p-TsOH / methanol / 16 h / 20 °C
6: 97 percent / Na(Hg); Na2HPO4 / methanol / 21 h / 20 °C
View Scheme
参考文献
Capdevila, Anna; Prasad, Attaluri R.; Quero, Carmen; Petschen, Ines; Bosch, Maria P.; Guerrero, Angel
Organic Letters, 1999 , vol. 1, # 6 p. 845 - 848
反应条件
1: tetrahydrofuran / 0.33 h / 20 °C
2: LiBr / tetrahydrofuran; hexamethylphosphoric acid triamide / 2 h / Heating
3: 81 percent / dimethylformamide / 4 h / 110 °C
4: 66 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 - -50 °C
5: 84 percent / p-TsOH / methanol / 16 h / 20 °C
6: 97 percent / Na(Hg); Na2HPO4 / methanol / 21 h / 20 °C
7: 83 percent / Na; NH3 / tetrahydrofuran / 4 h
8: 95 percent / DMAP; Et3N / CH2Cl2
View Scheme
参考文献
Capdevila, Anna; Prasad, Attaluri R.; Quero, Carmen; Petschen, Ines; Bosch, Maria P.; Guerrero, Angel
Organic Letters, 1999 , vol. 1, # 6 p. 845 - 848
反应条件
1: 65 percent / pyridine, phosphorus tribromide / benzene / 6 h / Heating
2: tetrahydrofuran / Ambient temperature
3: 1.) sodium hexamethyldisilazylamide / 1.) THF, RT, 1 h, 2.) THF, from -60 to -40 deg C, 5 h
View Scheme
参考文献
Matveeva, E. D.; Kvasha, M. P.; Kurts, A.L.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 7.1 p. 1017 - 1021
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 7 p. 961 - 965
