4-咪唑-1-丁烷-2-酮合成路线 （共 3 条）
反应条件
aluminum oxide; cerium(III) chloride; sodium iodide
T=35°C; Michael addition; 24 h;
参考文献
Yacob, Zekarias; Liebscher, Juergen
Arkivoc, 2012 , vol. 2012, # 3 p. 312 - 319
反应条件
1H-imidazole in dimethyl sulfoxide
T=70°C; 1 h;
参考文献
Bo, Kai Liu; Wu, Qi; Xue, Qi Qian; De, Shui Lv; Xian, Fu Lin
Synthesis, 2007 , # 17 p. 2653 - 2659
反应条件
1: formaldehyd; acetone With pyrrolidine; L-proline in dimethyl sulfoxide
Mannich reaction;
2: 1H-imidazole in ethanol; water
5 h;
参考文献
Bhandari, Kalpana; Srinivas, Nagarapu; Marrapu, Vijay K.; Verma, Aditya; Srivastava, Saumya; Gupta, Suman
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 291 - 293
