(2S,3R)-3-氨基-2-羟基-4-苯丁酸合成路线 （共 35 条）
反应条件
lithium hydroxide in methanol; water
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
2: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 95 percent / KH / dimethylformamide; benzene 2: 80 percent / I2 3: 1.) AgOAc, 2.) 1N NaOH / 1.) DMF, AcOH, 2.)MeOH, H2O 4: 82 percent / Na / NH3 6: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 82 percent / Na / NH3 3: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 1.) DIBAH, 2.) KH / 1.) toluene, 2.) toluene and THF 2: 95 percent / KH / dimethylformamide; benzene 3: 80 percent / I2 4: 1.) AgOAc, 2.) 1N NaOH / 1.) DMF, AcOH, 2.)MeOH, H2O 5: 82 percent / Na / NH3 7: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 80 percent / I2 2: 1.) AgOAc, 2.) 1N NaOH / 1.) DMF, AcOH, 2.)MeOH, H2O 3: 82 percent / Na / NH3 5: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 1.) AgOAc, 2.) 1N NaOH / 1.) DMF, AcOH, 2.)MeOH, H2O 2: 82 percent / Na / NH3 4: 2N LiOH / methanol; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 44 p. 5079 - 5082
反应条件
1: 84 percent / K2CO3 / methanol; H2O / 24 h / Ambient temperature 2: 82 percent / Na-naphthalide / 1,2-dimethoxy-ethane / 0.5 h / -78 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 79, # 4 p. 1203 - 1216
反应条件
hydrogenchloride in ethanol; water 8 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 16, # 18 p. 3124 - 3127
反应条件
1: 78 percent / BF3*Et2O / 0 - 20 °C 2: hydrochloric acid / H2O; ethanol / 8 h / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 16, # 18 p. 3124 - 3127
