(3R,4R)-1-[(叔丁氧基)羰基]-4-(乙氧基羰基)吡咯烷-3-羧酸合成路线 （共 3 条）
反应条件
sodium hydroxide; Lipase OF; sodium chloride in phosphate buffer
pH=7.5; 40 h;
参考文献
Rodriguez Sarmiento, Rosa Maria; Wirz, Beat; Iding, Hans
Tetrahedron Asymmetry, 2003 , vol. 14, # 11 p. 1547 - 1551
反应条件
1: H2 / Pd/C / ethanol / 5.5 h
2: 46.4 percent / aq. NaCl; hydrolase ESP-ESL 1199; aq. NaOH / aq. phosphate buffer / pH 7.0
3: 100 percent / aq. NaCl; lipase OF; aq. NaOH / aq. phosphate buffer / 40 h / pH 7.5
View Scheme
参考文献
Rodriguez Sarmiento, Rosa Maria; Wirz, Beat; Iding, Hans
Tetrahedron Asymmetry, 2003 , vol. 14, # 11 p. 1547 - 1551
反应条件
1: toluene / Heating
2: H2 / Pd/C / ethanol / 5.5 h
3: 46.4 percent / aq. NaCl; hydrolase ESP-ESL 1199; aq. NaOH / aq. phosphate buffer / pH 7.0
4: 100 percent / aq. NaCl; lipase OF; aq. NaOH / aq. phosphate buffer / 40 h / pH 7.5
View Scheme
参考文献
Rodriguez Sarmiento, Rosa Maria; Wirz, Beat; Iding, Hans
Tetrahedron Asymmetry, 2003 , vol. 14, # 11 p. 1547 - 1551
