N-甲基-4-溴-2-甲基苯胺合成路线 (共 2 条)
反应条件
1: With potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 14 h; 2: With ammonium chloride in DMF (N,N-dimethyl-formamide); water
参考文献
US2003/229093 A1, ;
Page 14 ;
US 20030229093 A1
反应条件
N-bromosuccinmide in acetonitrile T=20°C; 3 h;
参考文献
Mordant, Celine; Schmitt, Benoit; Pasquier, Elisabeth; Demestre, Christophe; Queguiner, Laurence; Masungi, Chantal; Peeters, Anik; Smeulders, Liesbeth; Bettens, Eva; Hertogs, Kurt; Heeres, Jan; Lewi, Paul; Guillemont, Jerome
European Journal of Medicinal Chemistry, 2007 , vol. 42, # 5 p. 567 - 579