4-溴-3,5-二甲基苯胺合成路线 （共 15 条）
反应条件
1: With acetic anhydride; triethylamine in chloroform T=20°C; 4 h; 2: With N-bromosuccinmide in acetonitrile T=20°C; 12 h; 3: With hydrogenchloride; water in ethanol 6 h; Heating;
参考文献
Toyota, Kozo; Kawasaki, Subaru; Yoshifuji, Masaaki
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 5065 - 5070
反应条件
sodium hydroxide in ethanol 6 h; Heating;
参考文献
Rodriguez, Gema; Albrecht, Martin; Schoenmaker, Jeroen; Ford, Alan; Lutz, Martin; Spek, Anthony L.; Van Koten, Gerard
Journal of the American Chemical Society, 2002 , vol. 124, # 18 p. 5127 - 5138
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2995,3001
反应条件
1: water; ammonia / 180 °C 2: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr 3: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2995,3001
反应条件
1: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr 2: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2995,3001
反应条件
1: nitric acid 2: sulfuric acid 3: aq.-ethanolic H2SO4 / Diazotization.Kochen der Diazoniumsalz-Loesung 4: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2995,3001
反应条件
1: aq.-ethanolic H2SO4 / Diazotization.Kochen der Diazoniumsalz-Loesung 2: tin (II)-chloride; aq.-ethanolic hydrochloric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 62, p. 2995,3001
反应条件
1.1: hydrogen / palladium 10 on activated carbon / methanol / 16 h / 20 °C 2.1: n-butyllithium / hexane; tetrahydrofuran / 0.58 h / -78 - -40 °C 2.2: 2.5 h / -78 °C 2.3: 2.5 h / -78 - 0 °C View Scheme
反应条件
1: With sulfuric acid; sodium nitrite in acetic acid T=0 - 10°C; 1 h; 2: With hydrogen bromide; copper(I) bromide in acetic acid T=70°C; Sandmeyer reaction; 2 h;
参考文献
Toyota, Kozo; Kawasaki, Subaru; Yoshifuji, Masaaki
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 5065 - 5070
