4-溴-3,5-二甲基苯胺合成路线 （共 15 条）
参考文献
Haning, Helmut; Schmidt, Gunter; Pernerstorfer, Josef; Bischoff, Hilmar; Schmeck, Carsten; Vohringen, Verena; Woltering, Michael; Kretschmer, Axel; Faeste, Christiane
Patent: US2003/203898 A1, 2003 ;
反应条件
in dichloromethane
T=0 - 20°C;
参考文献
Sung, Moo Je; Coppola, Gary Mark; Yoon, Taeyoung; Gilmore, Thomas A.
Patent: US2011/46133 A1, 2011 ;
Location in patent: Page/Page column 60 ;
反应条件
1.1: sulfuric acid; sodium nitrite / water / 0.42 h / -10 °C / Inert atmosphere
1.2: 2.33 h / -10 - 0 °C / Inert atmosphere
2.1: palladium diacetate; sodium carbonate; triphenylphosphine; 3,4,5-trimethoxyphenylboronic acid / water; acetone / 18 h / Reflux; Inert atmosphere
View Scheme
参考文献
Fujihara, Tetsuaki; Tomike, Yoshikazu; Ohtake, Toshiyuki; Terao, Jun; Tsuji, Yasushi
Chemical Communications, 2011 , vol. 47, # 34 p. 9699 - 9701
反应条件
1: With sulfuric acid; sodium nitrite in water
T=-10°C; 0.416667 h; Inert atmosphere;
2: With potassium iodide in water
T=-10 - 0°C; 2.33 h; Inert atmosphere;
参考文献
Fujihara, Tetsuaki; Tomike, Yoshikazu; Ohtake, Toshiyuki; Terao, Jun; Tsuji, Yasushi
Chemical Communications, 2011 , vol. 47, # 34 p. 9699 - 9701
反应条件
dihydrogen peroxide in methanol
T=0 - 20°C; 3 h;
参考文献
Kalypsys, Inc.
Patent: US2005/234046 A1, 2005 ;
Location in patent: Page/Page column 94 ;
US 20050234046 A1
