5-(2-苯基)乙基-1H-吡唑-3-羧酸乙酯合成路线 （共 2 条）
反应条件
hydrazine in ethanol; water
T=20°C; Heating / reflux;
参考文献
SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 16 ;
反应条件
1: EtONa / ethanol / 18 h / 20 °C
2: N2H4*H2O; AcOH / 8 h / Heating
View Scheme
参考文献
Van Herk; Brussee; Van den Nieuwendijk; Van der Klein; IJzerman; Stannek; Burmeister; Lorenzen
Journal of Medicinal Chemistry, 2003 , vol. 46, # 18 p. 3945 - 3951
