4-(2-吡啶基)苯甲醚合成路线 （共 81 条）
反应条件
N-methylamine hydrochloride; methylamine in ethanol T=140°C; 40 h;
参考文献
Blokhin, A. V.; Tyurekhodzhaeva, M. A.; Bazhenov, D. V.; Bobrovskii, S. I.; Bundel', Yu. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1990 , vol. 26, # 9 p. 1022 - 1025
Khimiya Geterotsiklicheskikh Soedinenii, 1990 , vol. 26, # 9 p. 1226 - 1229
反应条件
[Ni0(1,5-cyclooctadiene)2]; 1,1,3,3-tetramethyldisiloxane; tri-cyclo-hexyl-phosphine in toluene T=110°C; 10 h; Inert atmosphere;
参考文献
Alvarez-Bercedo, Paula; Martin, Ruben
Journal of the American Chemical Society, 2010 , vol. 132, # 49 p. 17352 - 17353
反应条件
chromium(VI) oxide; acetic anhydride; acetic acid; copper(II) oxide; lithium bromide T=150°C; 17 h; sealed tube; regioselective reaction;
参考文献
Synlett, , # 7 p. 1038 - 1042
反应条件
NHC-Pd(II)-Im; potassium tert-butylate in water
T=80°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong
Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water; toluene
12 h; Inert atmosphereReflux;
参考文献
Kim, Ji Young; Park, Sae Hume; Ryu, Jaeyune; Cho, Seung Hwan; Kim, Seok Hwan; Chang, Sukbok
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9110 - 9113
反应条件
[1,3-bis(2,6-diisopropylphenyl)-imidazolium][Ni(PPh3)Cl3] in tetrahydrofuran
T=30°C; Kumada Cross-Coupling; 5 h; Schlenk techniqueInert atmosphere;
参考文献
Xu, Yan-Chao; Zhang, Jie; Sun, Hong-Mei; Shen, Qi; Zhang, Yong
Dalton Transactions, 2013 , vol. 42, # 23 p. 8437 - 8445
反应条件
C35H31BrN4NiP in tetrahydrofuran
T=25°C; 11 h; Schlenk techniqueInert atmosphere;
参考文献
Guo, Wang-Jun; Wang, Zhong-Xia
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1054 - 1061
反应条件
C32H26ClN2NiP in tetrahydrofuran
T=30°C; Kumada Cross-Coupling; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Zhang, Xue-Qi; Wang, Zhong-Xia
Synlett, 2013 , vol. 24, # 16 art. no. ST-2013-W0528-L, p. 2081 - 2084
反应条件
copper(l) iodide; C37H51ClFeNPPd; cesium fluoride in N,N-dimethyl-formamide
T=80°C; Stille Cross Coupling; 12 h; Inert atmosphere;
参考文献
Ma, Gaizhi; Leng, Yuting; Wu, Yusheng; Wu, Yangjie
Tetrahedron, 2013 , vol. 69, # 2 p. 902 - 909
反应条件
PinP(O)H; [Pd(dibenzylideneacetone)2] in tetrahydrofuran; 1,4-dioxane
T=80°C; Kumada cross-coupling reaction; 22 h;
参考文献
Ackermann, Lutz; Althammer, Andreas
Organic Letters, 2006 , vol. 8, # 16 p. 3457 - 3460
