4-(2-吡啶基)苯甲醚合成路线 （共 81 条）
反应条件
diethyl ether
Anschliessend mit Luft;
参考文献
Gilman; Edward
Canadian Journal of Chemistry, 1953 , vol. 31, p. 457,466
Full Text Show Details
Papa et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 1279
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; silver(l) oxide in tetrahydrofuran; N,N-dimethyl-formamide
T=90°C; 18 h;
参考文献
Napier, Spencer; Marcuccio, Sebastian M.; Tye, Heather; Whittaker, Mark
Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6314 - 6315
反应条件
copper(l) iodide; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide
T=100°C; 22 h; Inert atmosphere;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Heterocycles, 2010 , vol. 80, # 1 p. 359 - 368
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in toluene
12 h; RefluxInert atmosphere;
参考文献
Xu, Jimin; Cheng, Guolin; Su, Deyong; Liu, Yantao; Wang, Xinyan; Hu, Yuefei
Chemistry - A European Journal, 2009 , vol. 15, # 47 p. 13105 - 13110
反应条件
1: triethylamine / tetrahydrofuran / 18 h / 0 - 20 °C / |Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol / 18 h / 100 °C / |Inert atmosphere
View Scheme
参考文献
Goggins, Sean; Rosevere, Eleanor; Bellini, Clement; Allen, Joseph C.; Marsh, Barrie J.; Mahon, Mary F.; Frost, Christopher G.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 47 - 52
反应条件
1.1: dichloromethane / 0.5 h / 20 °C / |Inert atmosphere
1.2: 0.25 h / 20 °C / |Inert atmosphere
2.1: triethylamine / tetrahydrofuran / 18 h / 0 - 20 °C / |Inert atmosphere
3.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol / 18 h / 100 °C / |Inert atmosphere
View Scheme
参考文献
Goggins, Sean; Rosevere, Eleanor; Bellini, Clement; Allen, Joseph C.; Marsh, Barrie J.; Mahon, Mary F.; Frost, Christopher G.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 47 - 52
反应条件
1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere; |Schlenk technique
1.2: -78 - 20 °C / |Inert atmosphere; |Schlenk technique
2.1: hydrogenchloride / water / 20 °C / |Inert atmosphere; |Schlenk technique
3.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene; ethanol / 20 h / |Inert atmosphere; |Schlenk technique; |Reflux
View Scheme
参考文献
Zhou, Bingwei; Chen, Hui; Wang, Congyang
Journal of the American Chemical Society, 2013 , vol. 135, # 4 p. 1264 - 1267
反应条件
2,2'-azo-bisisobutyronitrile; tris-(trimethylsilyl)silane; acetic acid
T=80°C; 32 h;
参考文献
Nunez, Araceli; Sanchez, Aranzazu; Burgos, Carolina; Alvarez-Builla, Julio
Tetrahedron, 2004 , vol. 60, # 29 p. 6217 - 6224
反应条件
in N,N-dimethyl-formamide
Ambient temperature; Yield given;
参考文献
Gosmini, Corinne; Lasry, Sarah; Nedelec, Jean-Yves; Perichon, Jacques
Tetrahedron, 1998 , vol. 54, # 7 p. 1289 - 1298
反应条件
1: CH2Cl2 / 10 h / Ambient temperature; Irradiation
2: diethyl ether / Ambient temperature
View Scheme
参考文献
Terashima, Masanao; Seki, Koh-ichi; Yoshida, Chihiro; Ohkura, Kazue; Kanaoka, Yuichi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1009 - 1015
