2-甲基-1-(2-哌啶基)-1-丙酮合成路线 （共 12 条）
反应条件
tert.-butylhydroperoxide; tetrabutyl-ammonium chloride; sodium carbonate; copper dichloride; BQC in water T=40°C; 48 h;
参考文献
Boudreau, Josee; Doucette, Mike; Ajjou, Abdelaziz Nait
Tetrahedron Letters, 2006 , vol. 47, # 11 p. 1695 - 1698
反应条件
1: in diethyl ether T=-15 - 20°C; 4 h; 2: With hydrogenchloride in diethyl ether T=20°C; 0.25 h;
参考文献
Easmon, Johnny; Puerstinger, Gerhard; Thies, Katrin-Sofia; Heinisch, Gottfried; Hofmann, Johann
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6343 - 6350
反应条件
potassium hydroxide; 18-crown-6 ether in toluene 19 h; Ambient temperature;
参考文献
Rubina, K.; Goldberg, Yu.; Shymanska, M.
Synthetic Communications, 1989 , vol. 19, # 13-14 p. 2489 - 2500
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; oxygen in dimethyl sulfoxide 3 h;
参考文献
Donetti, Arturo; Boniardi, Orazio; Ezhaya, Antoine
Synthesis, 1980 , # 12 p. 1009 - 1011
反应条件
in tetrahydrofuran T=20°C; 4 h; Inert atmosphere;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron Letters, 2009 , vol. 50, # 38 p. 5329 - 5331
Title/Abstract Full Text View citing articles Show Details
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron, 2010 , vol. 66, # 17 p. 3135 - 3146
反应条件
in diethyl ether 0.5 h;
参考文献
Voinov, M. A.; Volodarsky, L. B.
Russian Chemical Bulletin, 1997 , vol. 46, # 1 p. 126 - 132
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1997 , # 1 p. 131 - 136
反应条件
1: 72 percent / triethylbenzylammonium chloride, aq. sodium hydroxide / overnight 2: 55 percent / aq. sodium hydroxide, triethylbenzylammonium chloride / toluene / 24 h View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 1061 - 1065
反应条件
1: tetrahydrofuran / 3 h / -20 °C 2: tert.-butylhydroperoxide; CuCl2·2H2O; sodium carbonate; BQC / water / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 12 p. 2808 - 2810
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; oxygen 1.) room temp., 2.) DMSO, 3 h; Yield given. Multistep reaction;
参考文献
Synthesis, , # 12 p. 1009 - 1011
反应条件
1: 95 percent / Br2 / acetic acid; diethyl ether / 72 h 2: 75 percent / NH2OH / H2O; methanol / 2 h / Heating View Scheme
参考文献
Voinov, M. A.; Volodarsky, L. B.
Russian Chemical Bulletin, 1997 , vol. 46, # 1 p. 126 - 132
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 1997 , # 1 p. 131 - 136
