乙基(2E)-3-(3-吡啶基)丙烯酸酯合成路线 (共 37 条)
反应条件
sodium hydrogencarbonate; triphenylphosphine T=20°C; Wittig reaction; 1 h; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 72, # 14 p. 5244 - 5259
反应条件
1,10-phenanthroline; palladium diacetate; silver carbonate in N,N-dimethyl-formamide T=140°C; 12 h;
参考文献
Journal of the American Chemical Society, , vol. 133, # 18 p. 6964 - 6967
反应条件
1,10-phenanthroline; palladium diacetate; silver carbonate in N,N-dimethyl-formamide T=140°C; 12 h;
参考文献
Journal of the American Chemical Society, , vol. 133, # 18 p. 6964 - 6967
反应条件
aluminum oxide T=25°C; 0.5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Chemical Research, Synopses, , # 10 p. 414 - 415
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 65 - 72
反应条件
ethanol; sulfuric acid
参考文献
Helvetica Chimica Acta, , vol. 24, p. 24 E, 25 E
反应条件
1: 87 percent / H2 / 5percent rhodium on aluminum oxide / ethanol / 12 h / 60 °C / 3102.9 Torr View Scheme
参考文献
Zarrinmayeh, Hamideh; Nunes, Anne M.; Ornstein, Paul L.; Zimmerman, Dennis M.; Arnold, M. Brian; Schober, Douglas A.; Gackenheimer, Susan L.; Bruns, Robert F.; Hipskind, Philip A.; Britton, Thomas C.; Cantrell, Buddy E.; Gehlert, Donald R.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 15 p. 2709 - 2719
反应条件
diisobutylaluminium hydride in toluene 15 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 56, # 5 p. 1922 - 1927
反应条件
lithium hydroxide in 1,4-dioxane 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 3 p. 320 - 330
反应条件
1: DIBAL / toluene / 0.33 h / 0 °C 2: MnO2 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Oida, Sadao; Tajima, Yawara; Konosu, Toshiyuki; Nakamura, Yoshie; Somada, Atsushi; Tanaka, Teruo; Habuki, Shinobu; Harasaki, Tamako; Kamai, Yasuki; Fukuoka, Takashi; Ohya, Satoshi; Yasuda, Hiroshi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 5 p. 694 - 707