5'-O-三苯甲基-2',3'-去氢胸苷合成路线 （共 25 条）
反应条件
1: pyridine 2: 12 percent / NaOH View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2695 - 2698
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2695 - 2698
反应条件
acetic acid T=50°C; 1 h;
参考文献
Ewing; Glacon; Mackenzie; Postel; Len
Tetrahedron, 2003 , vol. 59, # 7 p. 941 - 945
反应条件
1: 42 percent / N-bromoacetamide / acetone / 1.) 0 deg C, 1 h, 2.) room temperature, 2 h
2: 85.3 percent / NaHCO3, Ph3P / dimethylformamide / 0.17 h
3: 93 percent / NaOH / acetone / 0.33 h
View Scheme
参考文献
Minamoto, Katsumaro; Oishi, Masataka; Kakehi, Akikazu; Ohta, Naoki; Matsuda, Isamu; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 16 p. 2289 - 2296
反应条件
2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexane
T=-70°C; 0.25 h; Product distribution;
参考文献
Kumamoto, Hiroki; Tanaka, Hiromichi
The Journal of organic chemistry, 2002 , vol. 67, # 11 p. 3541 - 3547
