6,7-二氢-5H-吡咯[1,2-a]咪唑合成路线 （共 7 条）
反应条件
sodium iodide; methyloxirane in 1,4-dioxane; methanol; dichloromethane; butanone
参考文献
US5039691 A1, ;
US 5039691 A
反应条件
titanium tetrachloride in 1,3,5-trimethyl-benzene 90 h; Heating;
参考文献
Hua, Duy H.; Zhang, Fengqi; Chen, Jinshan; Robinson, Paul D.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5084 - 5087
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 6 h; Heating;
参考文献
Aldabbagh, Fawaz; Bowman, W. Russell
Tetrahedron, 1999 , vol. 55, # 13 p. 4109 - 4122
反应条件
1: With triethylamine in dichloromethane 2 h; Reflux; 2: in formic acid T=80°C; 20 h;
参考文献
Tseng, Ming-Chung; Tseng, Min-Jen; Chu, Yen-Ho
Chemical Communications, 2009 , # 48 p. 7503 - 7505
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 6 h; Heating;
参考文献
Tetrahedron, , vol. 55, # 13 p. 4109 - 4122
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 5 h; Heating;
参考文献
Aldabbagh, Fawaz; Bowman, W. Russell
Tetrahedron, 1999 , vol. 55, # 13 p. 4109 - 4122
反应条件
potassium carbonate; methyloxirane; sodium iodide 1.) 2-butanone, dioxane, reflux, 20 h, 2.) methanol, 25 deg C, 20 h; Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 23 p. 4415 - 4424
