glucose dehydrogenase; D-glucose; β-NADP+ T=30°C; pH=7.5; 24 h; aq. buffer; optical yield given as percent ee;

1: phenyllithium With copper (I) cyanide in tetrahydrofuran; diethyl ether; hexane T=-30 - -10°C; 0.166667 h; Inert atmosphere; 2: 1-chloro-1-methyl-2-(hydroxyimino)ethane in tetrahydrofuran; diethyl ether; hexane T=-30°C; 0.333333 h; Inert atmosphere; 3: With sulfuric acid in tetrahydrofuran; diethyl ether; hexane; dichloromethane T=-30°C; Inert atmosphere;

hydroxylamine hydrochloride; lithium carbonate T=20°C; 0.5 h;

glucose dehydrogenase; D-glucose; pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2; nicotinamide adenine dinucleotide T=30°C; pH=7.5; 24 h; aq. bufferEnzymatic reaction;

glucose dehydrogenase; D-glucose; OPR3 isoenzyme of 12-oxophytodienoate reductase from Lycopersicon esculentum; NADP T=30°C; pH=7.5; 24 h; aq. bufferEnzymatic reaction;

glucose dehydrogenase; xenobiotic reductase A from Pseudomonas putida; D-glucose; NADP T=30°C; pH=7.5; 24 h; aq. bufferEnzymatic reaction;

1: nitric acid / 0.33 h / 0 °C 2: triethylamine / chloroform / 3 h / 20 °C 3: glucose dehydrogenase; pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2; D-glucose; nicotinamide adenine dinucleotide / 24 h / 30 °C / pH 7.5 / aq. buffer; Enzymatic reaction View Scheme

1: nitric acid / 0.33 h / 0 °C 2: triethylamine / chloroform / 3 h / 20 °C 3: glucose dehydrogenase; xenobiotic reductase A from Pseudomonas putida; D-glucose; NADP / 24 h / 30 °C / pH 7.5 / aq. buffer; Enzymatic reaction View Scheme

1: nitric acid / 0.33 h / 0 °C 2: triethylamine / chloroform / 3 h / 20 °C 3: xenobiotic reductase B from Pseudomonas putida JLR11; Reduced nicotinamide-adenine dinucleotide / 24 h / 30 °C / pH 7.5 / aq. buffer; Enzymatic reaction View Scheme