1: 1,3-bis-(trifluoromethyl)-benzene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine; diisopropylamine in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere; 2: N,N-dimethyl-formamide T=-78°C; 0.5 h; Inert atmosphere; regioselective reaction;

hydrogenchloride; n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide

lithium diisopropyl amide in tetrahydrofuran; N,N-dimethyl-formamide

暂无反应条件数据

1: C14H20F3N2O5PS With sodium hexamethyldisilazane T=-78°C; 2: 2,4-di-(trifluoromethyl)-benzaldehyde 3 h; Heating;