[1-(2-氯-嘧啶-4-基)-哌啶-4-基]-氨基甲酸叔丁酯合成路线 (共 2 条)
反应条件
triethylamine in N,N-dimethyl-formamide
T=20°C; 18 h; Product distribution / selectivity;
参考文献
ALMAC DISCOVERY LIMITED; HARRISON, Timothy; BURKAMP, Frank; JORDAN, Linda; BELL, Mark; JANSSEN, Dominic; MIEL, Hugues; MCFARLAND, Mary
Patent: WO2012/69852 A1, 2012 ;
Location in patent: Page/Page column 60 ;
反应条件
hydrogen; acetic acid; palladium on activated charcoal in ethanol
T=20°C; 5 h;
参考文献
Aventis Pharma Deutschland GmbH
Patent: EP1479676 A1, 2004 ;
Location in patent: Page 48 ;
EP 1479676 A1