2,2-二甲基-3-氧代丁酸乙酯合成路线 （共 56 条）
反应条件
2-(tert-butyl)-1,1,3,3-tetramethylguanidine in diethyl ether Ambient temperature;
参考文献
Glenmark Pharmaceuticals S.A.
Patent: US2008/200501 A1, 2008 ;
Location in patent: Page/Page column 44 ;
反应条件
potassium carbonate; [bmim]BF4 in N,N-dimethyl-formamide T=20°C;
参考文献
Muthusamy, Sengodagounder; Gnanaprakasam, Boopathy
Tetrahedron Letters, 2005 , vol. 46, # 4 p. 635 - 638
反应条件
meta-chloroperoxybenzoic acid; APClt;C2Lys(C5N(1+))2C14gt;4; tri-n-butyl-tin hydride in dichloromethane; water T=10°C; dark;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1237 - 1246
反应条件
tetra-(n-butyl)ammonium iodide; potassium carbonate in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Viera, Ignacio; Manta, Eduardo; Gonzalez, Lucia; Mahler, Graciela
Tetrahedron Asymmetry, 2010 , vol. 21, # 5 p. 631 - 635
反应条件
4-phenyl-acetophenone; zinc; benzene T=150°C; Reagens 4: Toluol;
参考文献
Journal of the American Chemical Society, , vol. 66, p. 153
反应条件
chromium(II) acetate in acetonitrile
参考文献
Tetrahedron, , vol. 45, # 18 p. 5943 - 5954
反应条件
zinc in 1,4-dioxane; diethyl ether Substitution; 0.166667 h; Heating;
参考文献
Fotin; Shchepin; Vakhrin
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 9 p. 1278 - 1281
反应条件
2-(tert-butyl)-1,1,3,3-tetramethylguanidine in diethyl ether Ambient temperaturealkylation in the presence of base; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 2085 - 2090
反应条件
cobalt complex of 2,10-diethyl-3,9-dipropyl-1,4,8,11-tetraazaundeca-1,3,8,10-tetraene-1,11-diol electrolytic process;
参考文献
Chemistry Letters, , # 5 p. 835 - 838
反应条件
diethyl ether; triphenylmethyl-sodium
参考文献
Journal of the American Chemical Society, , vol. 63, p. 3158
Org. Reactions, , vol. 1, p. 288
