1-苯基哌嗪-2,3-二酮合成路线 （共 2 条）
反应条件
1: 2.) Et3N / 1.) CH2Cl2, 0 deg C, 2.) 45 min
2: 100 percent / HCl gas / ethyl acetate / 0.05 h / 0 °C
3: acetophenone, Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 1.) 0 deg C, 30 min, 2.) room temperature, 4 h
View Scheme
参考文献
Dinsmore, Christopher J.; Bergman, Jeffrey M.
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4131 - 4134
反应条件
1: 100 percent / HCl gas / ethyl acetate / 0.05 h / 0 °C
2: acetophenone, Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 1.) 0 deg C, 30 min, 2.) room temperature, 4 h
View Scheme
参考文献
Dinsmore, Christopher J.; Bergman, Jeffrey M.
Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4131 - 4134
