3-甲基吡啶-2-甲酸甲酯合成路线 （共 12 条）
反应条件
sulfuric acid Reflux;
参考文献
Yaremenko, Anatoliy G.; Volochnyuk, Dmitriy M.; Shelyakin, Vyacheslav V.; Grygorenko, Oleksandr O.
Tetrahedron, 2013 , vol. 69, # 33 p. 6799 - 6803
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in N,N-dimethyl-formamide T=100°C;
参考文献
Subramanyam, Chakrapani; Chattarjee, Sankar; Mallamo, John P.
Tetrahedron Letters, 1996 , vol. 37, # 4 p. 459 - 462
反应条件
N-chloro-succinimide; sodium methylate in tetrahydrofuran 16 h; Ambient temperature; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 63, # 22 p. 7840 - 7850
反应条件
1: 70 percent / HCl(g) / Heating 2: 65 percent / TEA / CH2Cl2 / 2 h / Ambient temperature 3: 50 percent / LiCl, PdCl2(PPh3)2 / dimethylformamide / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 4 p. 459 - 462
反应条件
1: 65 percent / TEA / CH2Cl2 / 2 h / Ambient temperature 2: 50 percent / LiCl, PdCl2(PPh3)2 / dimethylformamide / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 4 p. 459 - 462
反应条件
1: potassium hydroxide; water 2: sulfuric acid / |Reflux View Scheme
参考文献
Tetrahedron, , vol. 69, # 33 p. 6799 - 6803
反应条件
hydrogenchloride; selenium(IV) oxide 1.) H2O, reflux, 20 h, 2.) reflux, 8 h; Yield givenMultistep reaction;
参考文献
Organic Preparations and Procedures International, , vol. 31, # 1 p. 120 - 123
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 0 - 20 °C 2: trichlorophosphate / 1,2-dichloro-ethane / 4 h / |Reflux View Scheme
参考文献
Lim, Chae Jo; Kim, Ji Young; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 6 p. 1736 - 1739
反应条件
1.1: N-bromosuccinmide / tetrachloromethane / 16 h / |Reflux 2.1: hydrazine hydrate / methanol / 5 h / |Reflux 3.1: trifluoroacetic acid; hydrogen; platinum(IV) oxide / 48 h / 20 °C / 2585.81 Torr / |Autoclave 3.2: pH 7 / |Saturated solution View Scheme
参考文献
Yaremenko, Anatoliy G.; Volochnyuk, Dmitriy M.; Shelyakin, Vyacheslav V.; Grygorenko, Oleksandr O.
Tetrahedron, 2013 , vol. 69, # 33 p. 6799 - 6803
反应条件
1: dihydrogen peroxide; acetic acid / 24 h / 80 °C 2: nitric acid; sulfuric acid / 5.33 h / 95 - 100 °C View Scheme
参考文献
Zhou, Heng; Sun, Guanglong; Liu, Zenglu; Zhan, Xiaoping; Mao, Zhenmin
Heterocycles, 2013 , vol. 87, # 10 p. 2071 - 2079
