1: 2,5-dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine With potassium carbonate in dimethyl sulfoxide T=30°C; 1 h; Inert atmosphere; 2: benzyl bromide in dimethyl sulfoxide T=30°C; 24 h; Inert atmosphere;

1.1: dimethyl sulfoxide / 96 h / 120 °C / |Inert atmosphere 2.1: potassium carbonate / dimethyl sulfoxide / 1 h / 30 °C / |Inert atmosphere 2.2: 24 h / 30 °C / |Inert atmosphere View Scheme

acetic acid 4 h; Heating;