4,7-二甲氧基-2-甲基茚满-1-酮合成路线 （共 4 条）
反应条件
scandium tris(trifluoromethanesulfonate) in nitromethane
T=100°C; Friedel-Crafts acylation; 0.333333 h;
参考文献
Fillion, Eric; Lou, Tiantong; Liao, E-Ting; Wilsily, Ashraf
Organic Syntheses, 2012 , vol. 89, p. 115 - 125
反应条件
1: 61 percent / K2CO3 / dimethylformamide
2: 69 percent / Sc(OTf)3 / nitromethane / 0.33 h / 100 °C
View Scheme
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
1.1: piperidinium acetate / ethanol / 0.5 h
1.2: 57 percent / NaBH3CN / ethanol / 0 - 20 °C
2.1: 61 percent / K2CO3 / dimethylformamide
3.1: 69 percent / Sc(OTf)3 / nitromethane / 0.33 h / 100 °C
View Scheme
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
sodium hydroxide
1.) room temperature, 30 min, 2.) 70 deg C, 10 min;
参考文献
Kometani, Tadashi; Yoshii, Eiichi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1191 - 1196
