(R)-(-)-2-辛醇合成路线 （共 140 条）
反应条件
1: 2,6-dimethylpyridine 2: potassium tert-butylate / tetrahydrofuran / 0 °C 3: sulfuric acid; water / tetrahydrofuran / 20 - 55 °C / |Reflux View Scheme
参考文献
Kyasa, Shivakumar; Puffer, Benjamin W.; Dussault, Patrick H.
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3452 - 3456
反应条件
phenylphosphorus tetrachloride in chloroform
T=25°C; 0.0833333 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bay, Elliott; Bak, David A.; Timony, Peter E.; Leone-Bay, Andrea
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3415 - 3417
反应条件
1: triethylamine / 20 °C / Inert atmosphere
2: iron (III) acetylacetonate; chloro-trimethyl-silane / dichloromethane / 16 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ortega, Nuria; Feher-Voelger, Andres; Brovetto, Margarita; Padron, Juan I.; Martin, Victor S.; Martin, Tomas
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 963 - 972
反应条件
1: pyridine / 20 °C / Inert atmosphere
2: iron (III) acetylacetonate; chloro-trimethyl-silane / dichloromethane / 120 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ortega, Nuria; Feher-Voelger, Andres; Brovetto, Margarita; Padron, Juan I.; Martin, Victor S.; Martin, Tomas
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 963 - 972
反应条件
diethylamino-sulfur trifluoride in dichloromethane
variously O-substituted derivatives were also studied; Product distribution;
参考文献
Matsumura, Yasushi; Shimada, Toyomichi; Nakayama, Toshiaki; Urushihara, Masahiro; Asai, Tomoyuki; et al.
Tetrahedron, 1995 , vol. 51, # 32 p. 8771 - 8782
反应条件
T=140°C; orthoformic acid tris-<l-octyl-(2)-ester>;
参考文献
Hunter
Journal of the Chemical Society, 1924 , vol. 125, p. 1392
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran
T=0°C; 0.1 h;
参考文献
Cambie, Richard C.; Chambers, David; Lindsay, Barry G.; Rutledge, Peter S.; Woodgate, Paul D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 822 - 827
反应条件
1: triethylamine / 20 °C / Inert atmosphere
2: anhydrous iron chloride / dichloromethane / 0.08 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ortega, Nuria; Feher-Voelger, Andres; Brovetto, Margarita; Padron, Juan I.; Martin, Victor S.; Martin, Tomas
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 963 - 972
反应条件
1: pyridine / 20 °C / Inert atmosphere
2: iron (III) acetylacetonate; chloro-trimethyl-silane / dichloromethane / 120 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Ortega, Nuria; Feher-Voelger, Andres; Brovetto, Margarita; Padron, Juan I.; Martin, Victor S.; Martin, Tomas
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 963 - 972
反应条件
1: Bu3P / tetrahydrofuran / 20 °C
2: Br2 / CH2Cl2; triethylamine / 20 °C
View Scheme
参考文献
Sevrin, Mireille; Krief, Alain
Journal of the Chemical Society, Chemical Communications, 1980 , # 14 p. 656 - 657
