反应条件
1: N-methylamine hydrochloride; 1-methyl-2H-3,1-benzoxazine-2,4(1H)-dione With triethylamine in dichloromethane 2: 2-bromo acetyl bromide With phosphate buffer in dichloromethane T=5°C; pH=7; 3: With 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
参考文献
Clark, Rachel L.; Carter, Katharine C.; Mullen, Alexander B.; Coxon, Geoffrey D.; Owusu-Dapaah, George; McFarlane, Emma; Duong Thi, M. Dao; Grant, M. Helen; Tettey, Justice N.A.; Mackay, Simon P.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 624 - 627
