3-甲基-1,2-丁二烯合成路线 （共 178 条）
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in diethyl ether
参考文献
Creary,X.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1777 - 1783
反应条件
1: 1.)methyllithium, diisopropylamine / 1.)ether, HMPA, r.t., 2 h, 2.)ether, -10 deg C, 1 h
2: Bu3SnH / benzene / Heating
View Scheme
参考文献
Apparu, Marcel; Crandall, Jack K.
Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2125 - 2130
反应条件
catalyst: Ni(COD)2-Ph2P(CH2)3PPh2 in toluene
alkynylstannane and 1,2-diene (molar ratio 1:3) reacted in toluene in presence of Ni complex (0.05 equiv.) and phosphine (0.05 equiv.) at 50°C for 60 h; detd. by (119)Sn NMR spectra; PhC2CMe2C(CH2)SnMe3 and PhC2CH2C(SnMe3)CMe2 (96:4) obtained, total yield 37percent;
参考文献
Shirakawa, Eiji; Hiyama, Tamejiro
Journal of Organometallic Chemistry, 2002 , vol. 653, # 1-2 p. 114 - 121
反应条件
catalyst: Ni(COD)2-Ph2P(CH2)3PPh2 in toluene
alkynylstannane and 1,2-diene (molar ratio 1:3) reacted in toluene in presence of Ni complex (0.05 equiv.) and phosphine (0.05 equiv.) at 50°C for 60 h; detd. by (119)Sn NMR spectra; PhC2CMe2C(CH2)SnMe3 and PhC2CH2C(SnMe3)CMe2 (96:4) obtained, total yield 37percent;
参考文献
Shirakawa, Eiji; Hiyama, Tamejiro
Journal of Organometallic Chemistry, 2002 , vol. 653, # 1-2 p. 114 - 121
反应条件
tetraethyl ammonium fluoride
electrolysis;
参考文献
Becker, James Y.; Zinger, Baruch
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 395 - 402
参考文献
Becker, James Y.; Zinger, Baruch
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 395 - 402
参考文献
Mokijewski
Chem. Zentralbl., 1900 , vol. 71, # II p. 331
参考文献
Mokijewski
Chem. Zentralbl., 1890 , vol. 61, # II p. 331
反应条件
1: diethyl ether / 1.) -78 deg C, 2.) -30 deg C,
2: 120 h
View Scheme
参考文献
Halazy, S.; Hevesi, L.
Tetrahedron Letters, 1983 , vol. 24, # 26 p. 2689 - 2692
反应条件
in diethyl ether
T=30°C;
参考文献
Halazy, S.; Hevesi, L.
Tetrahedron Letters, 1983 , vol. 24, # 26 p. 2689 - 2692
