1: With Al-trifluoromethanesulfonyldiisobutylalane in diethyl ether T=25°C; Meerwein-Ponndorf-Verley reduction; 6 h; Inert atmosphere; 2: With hydrogenchloride; water in diethyl ether regioselective reaction;
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1: With sodium tetrahydroborate; malonic acid in tetrahydrofuran T=25°C; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; water 16 h; Heating; Further stages.;
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