2,4,6-三甲基苯硼酸合成路线 （共 68 条）
反应条件
cesium carbonate in isopropyl alcohol under Ar; i-PrOH added to mixt. of Hg acetate, B compd. and Cs2CO3; sealed; heated at 50-55°C (oil bath) for 12-20 h; cooled; solvent removed by rotary evapn.; extd. with toluene or toluene-THF; filtered; filtrate reduced to dryness by rotary evapn.; triturated with pentane; dried; recrystd. from THF-pentane; elem. anal.;
参考文献
Partyka, David V.; Gray, Thomas G.
Journal of Organometallic Chemistry, 2009 , vol. 694, # 2 p. 213 - 218
反应条件
sodium carbonate; palladium dichloride T=25 - 30°C; Suzuki-Miyaura type coupling reaction; 0.0833333 h;
参考文献
Bandgar; Patil
Tetrahedron Letters, 2005 , vol. 46, # 44 p. 7627 - 7630
反应条件
palladium diacetate; triphenylphosphine in tetrahydrofuran; methanol T=100°C; Suzuki coupling; 1 h;
参考文献
Lando, Vanusa R.; Monteiro, Adriano L.
Organic Letters, 2003 , vol. 5, # 16 p. 2891 - 2894
反应条件
copper(I) oxide; ammonium hydroxide; air in methanol T=20°C; 12 h;
参考文献
Angewandte Chemie - International Edition, , vol. 48, # 6 p. 1114 - 1116
反应条件
1: Inert atmosphere 2: bis(1,2-diphenylphosphino)benzene; copper (II) acetate monohydrate; lithium tert-butylate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere View Scheme
参考文献
Matsuda, Naoki; Hirano, Koji; Satoh, Tetsuya; Miura, Masahiro
Angewandte Chemie - International Edition, 2012 , vol. 51, # 15 p. 3642 - 3645
反应条件
copper(I) thiophene-2-carboxylate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane T=100°C; 12 h;
参考文献
Zhang, Zhihui; Liebeskind, Lanny S.
Organic Letters, 2006 , vol. 8, # 19 p. 4331 - 4333
反应条件
[{Rh(OH)(cod)}2]; potassium carbonate in 1,4-dioxane T=80°C; 4 h; Inert atmosphere;
参考文献
Anbarasan, Pazhamalai; Neumann, Helfried; Beller, Matthias
Angewandte Chemie - International Edition, 2011 , vol. 50, # 2 p. 519 - 522
反应条件
copper(I) oxide; oxygen; N-methyl-2-(methylamino)ethylamine in acetonitrile T=25°C; 12 h; Schlenk technique;
参考文献
Ye, Yong; Wang, Yanhua; Liu, Pengtang; Han, Fushe
Chinese Journal of Chemistry, 2013 , vol. 31, # 1 p. 27 - 30
反应条件
in tetrahydrofuran T=20°C; 0.166667 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 11 p. 1397 - 1400
反应条件
1: With KHF2 in methanol; water T=0 - 20°C; 0.0333333 h; Inert atmosphere; 2: With NOBF4 in acetonitrile T=20°C; 0.00833333 h; regioselective reaction;
参考文献
Molander, Gary A.; Cavalcanti, Livia N.
Journal of Organic Chemistry, 2012 , vol. 77, # 9 p. 4402 - 4413
