3-(4-氯苯基)-1H-吡唑合成路线 （共 13 条）
反应条件
1: 4-chlorobenzaldehyde With toluene-4-sulfonic acid hydrazide in acetonitrile T=20°C; 3 h; 2: With sodium hydroxide in acetonitrile T=20°C; 0.333333 h; 3: 1-vinyl-imidazole in acetonitrile T=50°C; 48 h;
参考文献
Aggarwal, Varinder K.; De Vicente, Javier; Bonnert, Roger V.
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5381 - 5383
反应条件
hydrazine hydrate in ethanol T=60°C; 0.5 h;
参考文献
Mishra, Haritosh; Mukherjee, Rabindranath
Journal of Organometallic Chemistry, 2006 , vol. 691, # 16 p. 3545 - 3555
反应条件
hydrazine monohydrochloride; water; toluene-4-sulfonic acid in 1,4-dioxane T=80°C; 0.5 h; Inert atmosphere;
参考文献
Levi, Lucilla; Boersch, Christina; Gers, Charlotte F.; Merkul, Eugen; Mueller, Thomas J. J.
Molecules, 2011 , vol. 16, # 11 p. 9340 - 9356
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1945 - 1950
反应条件
hydrazine hydrate in chloroform T=20°C;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 38, # 6 p. 668 - 676
反应条件
1.1: AcONa / ethanol / 0.75 h / Heating 1.2: ethanol / 1 h / Heating 2.1: 8 percent / POCl3 / 40 - 80 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
反应条件
hydraziniumdihydrochloride in ethanol 3 h; Heating; Yield given;
参考文献
Synthesis, , # 6/7 p. 690 - 691
反应条件
triethylamine in dichloromethane 24 h;
参考文献
Journal of Chemical Research, Miniprint, , # 7 p. 1701 - 1757
反应条件
trichlorophosphate T=40 - 80°C; Vilsmeier formylation;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
反应条件
1: 1.) lithium diisopropylamide / HMPT, THF, 1.) -78 deg C, 30 min, 2.) -78 deg C, 30 min, room temp., 3h 2: hydrazine dihydrochloride / ethanol / 3 h / Heating View Scheme
参考文献
Synthesis, , # 6/7 p. 690 - 691
