反应条件
1: 87 percent / 2.) dil. HCl / dimethylformamide / 4 h / Ambient temperature
2: 1.) LDA, 2.) p-toluenesulfonic acid / 1.) THF, -78 deg C, 15 min, 2.) THF, RT, 2 h
3: 39.7 percent / acetic acid / H2O; ethyl acetate
4: diethyl ether; methanol
View Scheme
参考文献
Ohta, Shunsaku; Tsujimura, Atsuhiko; Okamoto, Masao
Chemical & Pharmaceutical Bulletin, 1981 , vol. 29, # 10 p. 2762 - 2768
