反应条件
1: toluene / 0.75 h / -23 °C
2: 88 percent / diethyl ether / 1.5 h / -78 °C
3: 86 percent / NaOMe, oxalic acid / methanol / 1.) reflux, 12 h, 2.) room temp., 5 h
4: 94 percent / n-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C
5: 96 percent / POCl3, DMF / trichloroethene / Ambient temperature
6: 89 percent / H2, Li2CO3 / 5percent Pt/C, 5percent Pd/C / ethanol / 9 h / Ambient temperature; 1.) 6 h, 2.) 3 h
View Scheme
参考文献
Al-awar, Rima S.; Joseph, Sajan P.; Comins, Daniel L.
Journal of Organic Chemistry, 1993 , vol. 58, # 27 p. 7732 - 7739
