N-甲酰-L-甲硫氨酰-L-白氨酰-L苯丙氨酸合成路线 （共 20 条）
反应条件
1: 86 percent / ethyl N,N-diisopropylamine / dimethylformamide 2: 91 percent / Na2CO3 / dimethylformamide; H2O / 1.5 h View Scheme
参考文献
Tetrahedron, , vol. 41, # 4 p. 739 - 744
反应条件
1: 10percent diethylamine / dimethylformamide / 2 h 2: 86 percent / ethyl N,N-diisopropylamine / dimethylformamide 3: 91 percent / Na2CO3 / dimethylformamide; H2O / 1.5 h View Scheme
参考文献
Tetrahedron, , vol. 41, # 4 p. 739 - 744
反应条件
1: 0.5 h / Ambient temperature 2: 92 percent / DIEA / dimethylformamide / 0.25 h / Ambient temperature 3: 91 percent / potassium carbonate / H2O; dimethylformamide / 0.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 44, # 16 p. 5101 - 5108
反应条件
1: diethylamine / dimethylformamide / 0.5 h / Ambient temperature 2: 86 percent / dimethylformamide / 0.25 h / Ambient temperature 3: 91 percent / potassium carbonate / H2O; dimethylformamide / 0.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 44, # 16 p. 5101 - 5108
反应条件
1: 92 percent / DIEA / dimethylformamide / 0.25 h / Ambient temperature 2: 91 percent / potassium carbonate / H2O; dimethylformamide / 0.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 44, # 16 p. 5101 - 5108
反应条件
1: 86 percent / dimethylformamide / 0.25 h / Ambient temperature 2: 91 percent / potassium carbonate / H2O; dimethylformamide / 0.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 44, # 16 p. 5101 - 5108
反应条件
1: TFA; acetone 2: 96 percent / Et3N / 18 h / 20 °C 3: TFA; acetone 4: 95 percent / Et3N / 18 h / 20 °C 5: aq. HCl; acetone / dioxane 6: 95 percent / HCOONa; Ac2O / 1.33 h / 0 - 20 °C 7: 95 percent / aq. NaOH / methanol / 0.33 h / 20 °C View Scheme
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 26, # 4 p. 245 - 256
反应条件
1: TFA; acetone 2: 95 percent / Et3N / 18 h / 20 °C 3: aq. HCl; acetone / dioxane 4: 95 percent / HCOONa; Ac2O / 1.33 h / 0 - 20 °C 5: 95 percent / aq. NaOH / methanol / 0.33 h / 20 °C View Scheme
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 26, # 4 p. 245 - 256
反应条件
1: aq. HCl; acetone / dioxane 2: 95 percent / HCOONa; Ac2O / 1.33 h / 0 - 20 °C 3: 95 percent / aq. NaOH / methanol / 0.33 h / 20 °C View Scheme
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 26, # 4 p. 245 - 256
参考文献
Sklyarov; Sbitneva; Kopina; Sidorovich
Russian Journal of Bioorganic Chemistry, 2000 , vol. 26, # 4 p. 245 - 256
