4-(羟基甲基)-1-甲基吡咯烷-2-酮合成路线 （共 4 条）
反应条件
sodium tetrahydroborate in ethanol
1) 7.5 h (addition); 2) 14h room temp.;
参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
反应条件
hydrogen; 5 wt. ruthenium on carbon in water
T=20 - 200°C; P=37503.8 - 150015 Torr; 24 h; Autoclave; Product distribution / selectivity;
参考文献
BASF SE
Patent: US2011/251119 A1, 2011 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 54 percent / methanol / 1) 1h, 5-10 deg C; 2) 48 h room temp.
2: 78 percent / NaBH4 / ethanol / 1) 7.5 h (addition); 2) 14h room temp.
View Scheme
参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
反应条件
hydrogenchloride in dichloromethane
5.5 h; Ambient temperature;
参考文献
Zoretic; Barcelos; Jardin; Bhakta
Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 810 - 814
