4,N-二甲基-n-苯基苯磺酰胺合成路线 （共 37 条）
反应条件
potassium hydroxide; 1-n-butyl-3-methylimidazolium hexafluorophosphate
T=20°C; 1 h;
参考文献
Hu, Yi; Chen, Zhen-Chu; Le, Zhang-Gao; Zheng, Qin-Guo
Organic Preparations and Procedures International, 2004 , vol. 36, # 4 p. 347 - 351
反应条件
pyridine; copper diacetate in dichloromethane
6 h; Ambient temperature;
参考文献
Chan, Dominic M. T.
Tetrahedron Letters, 1996 , vol. 37, # 50 p. 9013 - 9016
反应条件
1: 84 percent / potassium carbonate / dimethylformamide / 48 h
2: 78 percent / Cs2CO3; PPh3; iodoethane / Pd(OAc)2; DMPU / acetonitrile / 20 h / Heating
View Scheme
参考文献
Wilhelm, Thorsten; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 18 p. 4053 - 4056
反应条件
1: 87 percent / pyridine / 4 h / 85 °C
2: 84 percent / potassium carbonate / dimethylformamide / 48 h
3: 78 percent / Cs2CO3; PPh3; iodoethane / Pd(OAc)2; DMPU / acetonitrile / 20 h / Heating
View Scheme
参考文献
Wilhelm, Thorsten; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 18 p. 4053 - 4056
反应条件
1: 87 percent / pyridine / 4 h / 85 °C
2: 84 percent / potassium carbonate / dimethylformamide / 48 h
3: 78 percent / Cs2CO3; PPh3; iodoethane / Pd(OAc)2; DMPU / acetonitrile / 20 h / Heating
View Scheme
参考文献
Wilhelm, Thorsten; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 18 p. 4053 - 4056
反应条件
ClAu(di(tert-butyl)(1,1′-biphenyl-2-yl)-phosphine); AgNTf2 in dichloromethane
T=25°C; 0.133333 h; Inert atmosphere; diastereoselective reaction;
参考文献
Dateer, Ramesh B.; Shaibu, Balagopal S.; Liu, Rai-Shung
Angewandte Chemie - International Edition, 2012 , vol. 51, # 1 p. 113 - 117
反应条件
pyridine; oxygen; copper(ll) bromide in dimethyl sulfoxide
T=100°C; 24 h; chemoselective reaction;
参考文献
Tang, Xiaodong; Huang, Liangbin; Qi, Chaorong; Wu, Xia; Wu, Wanqing; Jiang, Huanfeng
Chemical Communications, 2013 , vol. 49, # 54 p. 6102 - 6104
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
0.166667 h;
参考文献
Edwards; Stemerick; McCarthy
Tetrahedron Letters, 1990 , vol. 31, # 24 p. 3417 - 3420
反应条件
1.1: triphenylphosphine oxide; trifluoromethanesulfonic anhydride / CH2Cl2 / 0.33 h / 0 °C
1.2: 69 percent / triethylamine / CH2Cl2 / 0 - 20 °C
2.1: 92 percent / LHMDS / tetrahydrofuran / 6 h / 50 °C
View Scheme
参考文献
Wilden, Jonathan D.; Geldeard, Lynsey; Lee, Chieh C.; Judd, Duncan B.; Caddick, Stephen
Chemical Communications, 2007 , # 10 p. 1074 - 1076
反应条件
1: iodyl sulfate; acetic acid anhydride; H2SO4 / anschl. mit wss. NaBr
2: aq.-ethanolic KOH
View Scheme
参考文献
Beringer et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 2705,2707
Journal of the American Chemical Society, 1959 , vol. 81, p. 342,346
