N-对甲苯基-对甲苯磺胺合成路线 （共 64 条）
反应条件
n-butyllithium in tetrahydrofuran; hexane
0.5 h; Ambient temperature; Yields of byproduct given;
参考文献
Ono; Araya; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 5 p. 1373 - 1378
反应条件
1: 0.1 N HCl / tetrahydrofuran / 0.25 h / Ambient temperature
2: 51 percent / CH2Cl2 / 2 h / Ambient temperature
3: 1.43 g / AcOH, AcONa.3H2O, H2O, 7percent NaHCO3, HCl / dioxane / 3.5 h / 100 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 51 percent / CH2Cl2 / 2 h / Ambient temperature
2: 1.43 g / AcOH, AcONa.3H2O, H2O, 7percent NaHCO3, HCl / dioxane / 3.5 h / 100 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 51 percent / CH2Cl2 / 2 h / Ambient temperature
2: 1.43 g / AcOH, AcONa.3H2O, H2O, 7percent NaHCO3, HCl / dioxane / 3.5 h / 100 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 68 percent / CH2Cl2 / 1 h / Ambient temperature
2: 0.1 N HCl / tetrahydrofuran; diethyl ether / 1.08 h / Ambient temperature
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 10 mg / 0.1 N HCl / tetrahydrofuran; diethyl ether / 0.27 h / Ambient temperature
2: 51 percent / CH2Cl2 / 2 h / Ambient temperature
3: 1.43 g / AcOH, AcONa.3H2O, H2O, 7percent NaHCO3, HCl / dioxane / 3.5 h / 100 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 0.35 g / 1 N NaOH / dioxane / 72 h / Ambient temperature
2: 51 percent / CH2Cl2 / 2 h / Ambient temperature
3: 1.43 g / AcOH, AcONa.3H2O, H2O, 7percent NaHCO3, HCl / dioxane / 3.5 h / 100 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
sodium hydroxide; sodium hydrogencarbonate in ethanol
4 h; Heating; Yield given;
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether
2.25 h; Ambient temperature;
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
sodium hydroxide; sodium hydrogencarbonate in ethanol
4 h; Heating; Yield given;
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
