N-对甲苯基-对甲苯磺胺合成路线 （共 64 条）
反应条件
[(tris(3,5-dimethylpyrazol-1-yl)methane)Fe(NCMe)3](BF4)2 in dichloromethane
T=19.84°C; Overall yield = 60 percent; regioselective reaction;
参考文献
Liang, Shengwen; Jensen, Michael P.
Organometallics, 2012 , vol. 31, # 23 p. 8055 - 8058
反应条件
p-toluidine in dichloromethane
Ambient temperature;
参考文献
Schaumann, Ernst; Grabley, Susanne
Chemische Berichte, 1980 , vol. 113, # 3 p. 934 - 940
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether
1.08333 h; Ambient temperature;
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 1.24 g / 0.1 N HCl / tetrahydrofuran; diethyl ether / 2.25 h / Ambient temperature
2: 90 mg / 1 N NaOH, 7percent NaHCO3, MeOH / tetrahydrofuran / 2.1 h / 60 °C
View Scheme
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether
1.08333 h; Ambient temperature;
参考文献
Ono, Machiko; Tamura, Shinzo
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1453 - 1462
反应条件
1: 80 percent / diethyl ether / Ambient temperature
2: 24 percent / p-toluidine / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Schaumann, Ernst; Grabley, Susanne
Chemische Berichte, 1980 , vol. 113, # 3 p. 934 - 940
反应条件
1: silica gel
2: tris-(dibenzylideneacetone)dipalladium(0); potassium phosphate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine / 1,1-dimethylpropan-1-ol / 16 h / 80 °C / Inert atmosphere
View Scheme
参考文献
Shekhar, Shashank; Dunn, Travis B.; Kotecki, Brian J.; Montavon, Donna K.; Cullen, Steven C.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4552 - 4563
反应条件
1: potassium carbonate / acetonitrile
2: tris-(dibenzylideneacetone)dipalladium(0); potassium phosphate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine / 1,1-dimethylpropan-1-ol / 16 h / 80 °C / Inert atmosphere
View Scheme
参考文献
Shekhar, Shashank; Dunn, Travis B.; Kotecki, Brian J.; Montavon, Donna K.; Cullen, Steven C.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4552 - 4563
反应条件
1: dihydrogen peroxide; trichlorophosphate / water; acetonitrile / 25 °C
2: Amberlite IRA-400 OH(1-)-form / water; acetonitrile / 0.05 h / 25 °C
View Scheme
参考文献
Bahrami, Kiumars; Khodaei, Mohammad M.; Abbasi, Jamshid
Tetrahedron, 2012 , vol. 68, # 25 p. 5095 - 5101
反应条件
1.1: pyridine / 0.5 h / 20 - 100 °C / |Inert atmosphere
2.1: magnesium / diethyl ether / 0.17 h / |Inert atmosphere; |Reflux
2.2: 0.5 h / |Inert atmosphere; |Heating
3.1: FeCl3·6H2O / 4 h / 60 °C / |Inert atmosphere
View Scheme
参考文献
Bunce, Richard A.; Cain, Nicholas R.; Cooper, John G.
Organic Preparations and Procedures International, 2013 , vol. 45, # 1 p. 28 - 43
