N,N-二甲基噻吩-3-羧酰胺合成路线 （共 4 条）
反应条件
n-butyllithium in diethyl ether; hexane 12 h;
参考文献
Chemische Berichte, , vol. 119, # 10 p. 3198 - 3203
反应条件
1: With 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane
T=20°C; 0.166667 h;
2: With triethylamine in dichloromethane
T=20°C; 15 h;
参考文献
MERCK PATENT GMBH
Patent: WO2008/11957 A1, 2008 ;
Location in patent: Page/Page column 52-53 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; N,N-dimethyl-formamide
T=85°C; 3 h;
参考文献
Tang, Dan-Tam D.; Collins, Karl D.; Ernst, Johannes B.; Glorius, Frank
Angewandte Chemie - International Edition, 2014 , vol. 53, # 7 p. 1809 - 1813
Angew. Chem., 2014 , vol. 126, # 07 p. 1840 - 1844,5
参考文献
Beimling, Peter; Kossmehl, Gerhard
Chemische Berichte, 1986 , vol. 119, # 10 p. 3198 - 3203
