1-乙氧基-3-三氟甲基-1,3-丁二烯合成路线 （共 52 条）
反应条件
1-n-butyl-3-methylimidazolium tetrafluoroborate T=25°C; 1 - 3 h;
参考文献
Buriol, Lilian; Frizzo, Clarissa P.; Marzari, Mara R. B.; Moreira, Dayse N.; Prola, Lizie D. T.; Zanatta, Nilo; Bonacorso, Helio G.; Martins, Marcos A. P.
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 6 p. 1037 - 1044
反应条件
sodium hydroxide in dichloromethane T=20°C; 0.25 h;
参考文献
Zanatta, Nilo; Squizani, Adriana M. C.; Fantinel, Leonardo; Nachtigall, Fabiane M.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synthesis, 2002 , # 16 p. 2409 - 2415
反应条件
sodium hydroxide T=22°C; 2 h;
参考文献
Gorbunova; Gerus; Galushko; Kukhar
Synthesis, 1991 , # 3 p. 207 - 209
反应条件
in acetonitrile Ambient temperature;
参考文献
Hojo, Masaru; Masuda, Ryoichi; Okada, Etsuji; Sakaguchi, Syuhei; Narumiya, Hitoshi; Morimoto, Katsushi
Tetrahedron Letters, 1989 , vol. 30, # 45 p. 6173 - 6176
反应条件
pyridine T=78°C; 15 h; Ionic liquid; Solvent; Overall yield = 44 percent; regioselective reaction;
参考文献
Martins, Marcos A. P.; Marzari, Mara R. B.; Frizzo, Clarissa P.; Zanatta, Marcileia; Buriol, Lilian; Andrade, Valquiria P.; Zanatta, Nilo; Bonacorso, Helio G.
European Journal of Organic Chemistry, 2012 , # 36 p. 7112 - 7119
反应条件
potassium hydroxide; water in benzene 1 h; Heating;
参考文献
Hojo, Masaru; Masuda, Ryoichi; Sakaguchi, Syuhei; Takagawa, Makoto
Synthesis, 1986 , # 12 p. 1016 - 1017
反应条件
in methanol T=55°C; 20 h; Cooling with ice; Overall yield = 63 percent; Overall yield = 153 g;
参考文献
SOLVAY SA; BRAUN, Max Josef; FISCHER, Reiner
Patent: WO2013/167586 A1, 2013 ;
Location in patent: Page/Page column 10 ;
反应条件
1: in ethanol T=50°C; 0.25 h; 2: With hydrogenchloride in diethyl ether 1 h; Heating; Further stages.;
参考文献
Schlosser, Manfred; Volle, Jean-Noel; Leroux, Frederic; Schenk, Kurt
European Journal of Organic Chemistry, 2002 , # 17 p. 2913 - 2920
反应条件
in dichloromethane 2 h; Heating;
参考文献
Pavlik, James W.; Ayudhya, Theppawut Israsena Na; Tantayanon, Supawan
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 6 p. 1087 - 1089
反应条件
hydrogenchloride in ethanol T=22°C; 48 h;
参考文献
Gerus, I. I.; Vdovenko, S. I.; Gorbunova, M. G.; Kukhar', V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 4 p. 398 - 406
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , # 4 p. 502 - 511
