5-氯苯并呋喃-2-甲酸乙酯合成路线 （共 6 条）
反应条件
potassium carbonate Cyclization;
参考文献
Owen; Nicholls; Smith; Whomsley
The Journal of pharmacy and pharmacology, 1999 , vol. 51, # 4 p. 427 - 433
反应条件
potassium carbonate T=140°C; 6 h;
参考文献
Onajole, Oluseye K.; Pieroni, Marco; Tipparaju, Suresh K.; Lun, Shichun; Stec, Jozef; Chen, Gang; Gunosewoyo, Hendra; Guo, Haidan; Ammerman, Nicole C.; Bishai, William R.; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 4093 - 4103
反应条件
1: KOH / ethanol / 0.75 h / Heating 2: sodium amalgam / aq. NaOH / 2.5 h View Scheme
参考文献
Chapleo, Christopher B.; Myers, Peter L.; Butler, Richard C. M.; Davis, John A.; Doxey, John C.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 570 - 576
反应条件
sodium hydroxide in tetrahydrofuran T=20°C;
参考文献
Piemontese, Luca; Carbonara, Giuseppe; Fracchiolla, Giuseppe; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio
Heterocycles, 2010 , vol. 81, # 12 p. 2865 - 2872
反应条件
1: LiAlH4 / tetrahydrofuran / Heating 2: Ph3P; DEAD / 20 °C View Scheme
参考文献
Kennis, Ludo E.J.; Bischoff, Francois P.; Mertens, Carolus J.; Love, Christopher J.; Van den Keybus, Frans A.F.; Pieters, Serge; Braeken, Mirielle; Megens, Anton A.H.P.; Leysen, Josee E.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 71 - 74
反应条件
1: NaOH / 20 °C 2: Cu; quinoline / 240 °C View Scheme
参考文献
Kennis, Ludo E.J.; Bischoff, Francois P.; Mertens, Carolus J.; Love, Christopher J.; Van den Keybus, Frans A.F.; Pieters, Serge; Braeken, Mirielle; Megens, Anton A.H.P.; Leysen, Josee E.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 71 - 74
