反应条件
1: 1.) cuprous iodide / 1.) cyclohexane, ether, THF, 0 deg C, 10 min; 2.) cyclohexane, ether, THF, RT, 2 h
2: sodium, liquid ammonia / tetrahydrofuran / 0.5 h / -78 °C
3: 30 percent HBr / methanol; acetic acid / Heating
4: NaHCO3 / methanol; H2O / Ambient temperature
5: O2, NaHCO3 / platinum(IV) oxide / H2O / 48 h / Ambient temperature
View Scheme
参考文献
Fuji, Kaoru; Kawabata, Takeo; Kiryu, Yoshimitsu; Sugiura, Yukio
Heterocycles, 1996 , vol. 42, # 2 p. 701 - 722
