1.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 2.1: dichloromethane / 1 h 3.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 4.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 20 °C / Inert atmosphere 6.1: methanol / 3 h 7.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 8.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 8.2: pH 3 9.1: dichloromethane / 2 h / 20 °C 10.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: dichloromethane / 1 h 2.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 3.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 20 °C / Inert atmosphere 5.1: methanol / 3 h 6.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 7.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 7.2: pH 3 8.1: dichloromethane / 2 h / 20 °C 9.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 20 °C / Inert atmosphere 3.1: methanol / 3 h 4.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 5.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 5.2: pH 3 6.1: dichloromethane / 2 h / 20 °C 7.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: methanol / 3 h 2.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 3.2: pH 3 4.1: dichloromethane / 2 h / 20 °C 5.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 2.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 2.2: pH 3 3.1: dichloromethane / 2 h / 20 °C 4.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: tetrahydrofuran / 0.5 h / 20 °C 2.1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C 3.1: ammonium acetate / 12 h / Reflux 4.1: potassium carbonate / ethanol; dichloromethane 5.1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 20 °C 6.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h 7.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 3 h / Inert atmosphere 8.1: BOP-Cl; triethylamine / acetonitrile / 3 h 9.1: triethylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere 10.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1 h / Inert atmosphere 11.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h 12.1: Dess-Martin periodane / dichloromethane / 2 h 13.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / tetrahydrofuran; water / 2 h 13.2: pH 2 14.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 15.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 15.2: pH 3 16.1: dichloromethane / 2 h / 20 °C 17.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h 2.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 3 h / Inert atmosphere 3.1: BOP-Cl; triethylamine / acetonitrile / 3 h 4.1: triethylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere 5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1 h / Inert atmosphere 6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h 7.1: Dess-Martin periodane / dichloromethane / 2 h 8.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / tetrahydrofuran; water / 2 h 8.2: pH 2 9.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 10.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 10.2: pH 3 11.1: dichloromethane / 2 h / 20 °C 12.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: methanol; water / 2 h 2.1: manganese(IV) oxide / acetonitrile / 24 h / 60 °C 3.1: dichloromethane / 1 h / Inert atmosphere 4.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 5.1: dichloromethane / 1 h 6.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 7.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 8.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 20 °C / Inert atmosphere 9.1: methanol / 3 h 10.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 11.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 11.2: pH 3 12.1: dichloromethane / 2 h / 20 °C 13.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme

1.1: sulfur trioxide pyridine complex / dichloromethane; dimethyl sulfoxide / 0.75 h 2.1: methanol; water / 2 h 3.1: manganese(IV) oxide / acetonitrile / 24 h / 60 °C 4.1: dichloromethane / 1 h / Inert atmosphere 5.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 6.1: dichloromethane / 1 h 7.1: benzotriazol-1-ol; triethylamine / dichloromethane / 0.03 h 8.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 9.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 20 °C / Inert atmosphere 10.1: methanol / 3 h 11.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere 12.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C 12.2: pH 3 13.1: dichloromethane / 2 h / 20 °C 14.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C View Scheme