1: 1,1-dioxo-3H-1,2-benzodithiol-3-one; 2-hydroxyethanethiol With water in acetonitrile thiolation; 0.166667 h; 2: diazomethane in diethyl ether T=24°C; Methylation; 0.0833333 h; Further byproducts given;
参考文献
Breydo, Leonid; Gates, Kent S.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 9 p. 885 - 889
potassium carbonate in dichloromethane T=20°C; 72 h;
参考文献
UNIVERSITY OF STRATHCLYDE; UNIVERSITY OF GLASGOW; HARNETT, Margaret; HARNETT, William; SUCKLING, Professor Colin J; SCOTT, Fraser; HUGGAN, Judith Kerr; KHALAF, Abedawn Ibrahim
Patent: WO2014/23934 A1, 2014 ;
Location in patent: Page/Page column 20 ;