反应条件
1: 2-hydroxyethanethiol With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0°C;
2: propargyl bromide in N,N-dimethyl-formamide; mineral oil
T=0 - 20°C;
参考文献
N.V. ORGANON; LOOZEN, Hubert, Jan, Jozef; TIMMERS, Cornelis, Marius; STOCK, Herman, Thijs
Patent: WO2011/12600 A1, 2011 ;
Location in patent: Page/Page column 55-56 ;
WO 2011/012600 A1