1: methylhydrazine With hydrogenchloride in ethanol T=0°C; 0.5 h; 2: ethyl 2-ethoxymethylidene-3-oxo-3-trifluoromethylpropionate in ethanol T=0°C; 18 h; 3: With sodium carbonate in ethanol; water
参考文献
PFIZER JAPAN INC.; PFIZER INC.; RENOVIS, INC.
Patent: WO2008/59370 A2, 2008 ;
Location in patent: Page/Page column 52 ;
WO 2008/059370 A2