甲基肼合成路线 - 魔法化学

参考文献

Chevron Research Company
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123367-27-1(E)-3-(二甲基氨基)-1-(吡啶-4-基)丙-2-烯-1-酮+

参考文献

GENENTECH, INC.; ARRAY BIOPHARMA, INC.; LAIRD, Ellen; LYSSIKATOS, Joseph, P.; WELCH, Mike; GRINA, Jonas; HANSEN, Josh; NEWHOUSE, Brad; OLIVERO, Alan; TOPOLAV, George
Patent: WO2006/84015 A2, 2006 ;
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WO 2006/084015 A2

60-34-4甲基肼+

325685-59-44-氯-6-(甲氧基甲基)-2-苯基嘧啶

922726-19-0

参考文献

Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763

60-34-4甲基肼+

325685-75-44-氯-6-羟基甲基-2-苯基嘧啶

922726-20-3

参考文献

Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie
Journal of the American Chemical Society, 2006 , vol. 128, # 51 p. 16748 - 16763

923972-90-1+

60-34-4甲基肼

923972-91-25-氨基-4-(2,6-二氯苯基)-1,2-二氢-2-甲基-3H-吡唑-3-酮

参考文献

KALYPSYS, INC.
Patent: WO2007/15866 A2, 2007 ;
Location in patent: Page/Page column 29; 31-32 ;
WO 2007/015866 A2

118431-89-33-环丁基-3-氧代-丙腈+

60-34-4甲基肼

92406-41-25-环丁基-2-甲基-2H-吡唑-3-胺

参考文献

Adachi; Yamamori; Hiramatsu; Sakai; Sato; Kawakami; Uno; Ueda
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 8 p. 3235 - 3252

21667-62-93-氯苯甲酰乙腈+

60-34-4甲基肼

92406-44-55-(3-氯苯基)-2-甲基-2H-吡唑-3-胺

参考文献

Boijeaf Gennaes, Gustav; Mologni, Luca; Ahmed, Shaheen; Rajaratnam, Mohanathas; Marin, Oriano; Lindholm, Niko; Viltadi, Michela; Gambacorti-Passerini, Carlo; Scapozza, Leonardo; Yli-Kauhaluoma, Jari
ChemMedChem, 2011 , vol. 6, # 9 p. 1680 - 1692

54123-21-63-氧代-3-(2-吡啶基)丙腈+

60-34-4甲基肼

92406-50-31-甲基-3-吡啶-2-基-1H-吡唑-5-胺

参考文献

ABBVIE INC.; Cusack, Kevin P.; Gordon, Thomas D.; Hoemann, Michael Z.; Ihle, David C.; Li, Bin; Lo Schiavo, Gloria Y.; Somal, Gagandeep K.; Friedman, Michael; Hayes, Martin E.; Bakker, Wouter Iwema
Patent: US2014/179676 A1, 2014 ;
Location in patent: Page/Page column ;

75358-91-7+

60-34-4甲基肼

93617-21-1

参考文献

Dunn, A.D.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 965 - 968

93715-00-5+

60-34-4甲基肼

93714-95-5

参考文献

Schmidpeter, Alfred; Willhalm, Angela
Angewandte Chemie, 1984 , vol. 96, # 11 p. 901 - 902