2-溴-2-甲基丙酸乙酯合成路线 （共 239 条）
反应条件
(i) NaOEt, EtOH, (ii) aq. NaOH; Multistep reaction;
参考文献
Vavrek; Ferger; Allen; Rich; Blomquist; Du Vigneaud
Journal of medicinal chemistry, 1972 , vol. 15, # 2 p. 123 - 126
参考文献
Shdanowitsch
Chem. Zentralbl., 1909 , vol. 80, # I p. 519
反应条件
in chloroform-d1 (N2 or Ar); 25°C, rapid mixing; determination by NMR;
参考文献
Canadian Journal of Chemistry, , vol. 68, # 3 p. 492 - 501
反应条件
in tetrahydrofuran (N2 or Ar); rapid mixing at room temp.;
参考文献
Canadian Journal of Chemistry, , vol. 68, # 3 p. 492 - 501
参考文献
Bloom; Hauser
Journal of the American Chemical Society, 1944 , vol. 66, p. 153
反应条件
(i) Mg, I2, THF, (ii) aq. NaOH, MeOCH2CH2OH; Multistep reaction;
参考文献
Dubois,J.C. et al.
Bulletin de la Societe Chimique de France, 1966 , p. 3008 - 3013
反应条件
potassium fluoride in N,N-dimethyl-formamide T=160°C; 1 h; Microwave irradiation;
参考文献
Schering Corporation and Pharmacopeia Drug Discovery, Inc.
Patent: US2007/93477 A1, 2007 ;
Location in patent: Page/Page column 31 ;
参考文献
Rothstein; Saville
Journal of the Chemical Society, 1949 , p. 1946,1949
参考文献
Weyerstahl,P. et al.
Justus Liebigs Annalen der Chemie, 1969 , vol. 725, p. 106 - 115
参考文献
Blaise; Marcilly
Bulletin de la Societe Chimique de France, 1904 , vol. <3>31, p. 111,113
