2-溴-2-甲基丙酸乙酯合成路线 （共 239 条）
反应条件
N(Et)4ClO4 in N,N-dimethyl-formamide
electrolysis, Hg cathode; other cathode, probases and conditions; Product distribution;
参考文献
Casadei, Maria Antonietta; Cesa, Stefania; Inesi, Achille
Tetrahedron, 1995 , vol. 51, # 20 p. 5891 - 5900
反应条件
1: 80 percent / zinc
2: n-butyllithium / diethyl ether / -35 °C
3: triethylamine / methanol / 12 h / Heating
View Scheme
参考文献
Slougui, N.; Rousseau, G.
Tetrahedron, 1985 , vol. 41, # 13 p. 2643 - 2652
反应条件
iodine; zinc in 1,4-dioxane
T=20°C; Reformatsky reaction; 0.0833333 h; sonication; Title compound not separated from byproducts.;
参考文献
Ross, Nathan A.; MacGregor, Robert R.; Bartsch, Richard A.
Tetrahedron, 2004 , vol. 60, # 9 p. 2035 - 2041
反应条件
zinc; benzene
Verseifen des entstehenden Aethylesters mit Barytwasser;
参考文献
Courtot
Bulletin de la Societe Chimique de France, 1906 , vol. <3>35, p. 121
Full Text Show Details
Bouveault
Bulletin de la Societe Chimique de France, 1899 , vol. <3>21, p. 1064
反应条件
hydrogenchloride; tetrabutylammomium bromide
1. DMF, a) voltage: 50 V, up to 50 deg C, b) voltage: 30 V, 50-60 deg C; anode: zinc rod, cathode: nickel net; Yield given. Multistep reaction;
参考文献
Schwarz, Karl-Heinz; Kleiner, Katharina; Ludwig, Ralf; Schick, Hans
Journal of Organic Chemistry, 1992 , vol. 57, # 14 p. 4013 - 4015
反应条件
tetrabutylammomium bromide in N,N-dimethyl-formamide
T=50 - 60°C; electrolysis with sacrificial indium anode;
参考文献
Schwarz, Karl-Heinz; Kleiner, Katharina; Ludwig, Rolf; Schick, Hans
Chemische Berichte, 1993 , vol. 126, # 5 p. 1247 - 1250
反应条件
sodium hydride in diethyl ether; dimethyl sulfoxide
参考文献
Bochenska,M.; Biernat,J.F.
Roczniki Chemii, 1976 , vol. 50, p. 1195 - 1199
反应条件
caesium carbonate in 1,4-dioxane
T=100°C; 4 h;
参考文献
Kuo, Gee-Hong; Zhang, Rui; Wang, Aihua; DeAngelis, Alan; Demarest, Keith; Pelton, Patricia
Patent: US2006/58382 A1, 2006 ;
Location in patent: Page/Page column 18 ;
US 20060058382 A1
反应条件
potassium tert-butylate in tetrahydrofuran
T=60°C; 2 h; Inert atmosphere;
参考文献
Oh, Lynette M.; Wang, Huan; Shilcrat, Susan C.; Hermann, Robert E.; Patience, Daniel B.; Spoors, P. Grant; Sisko, Joseph
Organic Process Research and Development, 2007 , vol. 11, # 6 p. 1032 - 1042
参考文献
Bischoff
Chemische Berichte, 1900 , vol. 33, p. 1254
