2-溴-2-甲基丙酸乙酯合成路线 （共 239 条）
反应条件
sodium hydride in toluene
参考文献
Leonardi; Rossi; Palmeri; Nardi; Subissi
Bollettino Chimico Farmaceutico, 1979 , vol. 118, # 5 p. 286 - 292
反应条件
T=160°C; Verseifen des erhaltenen Estergemisches;
参考文献
Bischoff; Mintz
Chemische Berichte, 1892 , vol. 25, p. 2324
反应条件
1: With bis(cyclopentadienyl)titanium dichloride; 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-diaza-2,5-cyclohexadiene in tetrahydrofuran
T=20°C; Reformatsky Reaction; 14 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; diethyl ether
Inert atmosphere;
参考文献
Saito, Teruhiko; Nishiyama, Haruka; Tanahashi, Hiromasa; Kawakita, Kento; Tsurugi, Hayato; Mashima, Kazushi
Journal of the American Chemical Society, 2014 , vol. 136, # 13 p. 5161 - 5170
反应条件
iodine; zinc in 1,4-dioxane
T=20°C; Reformatsky reaction; 0.0833333 h; sonication;
参考文献
Ross, Nathan A.; MacGregor, Robert R.; Bartsch, Richard A.
Tetrahedron, 2004 , vol. 60, # 9 p. 2035 - 2041
反应条件
iodine; zinc in 1,4-dioxane
T=20°C; Reformatsky reaction; 0.0833333 h; sonication;
参考文献
Ross, Nathan A.; MacGregor, Robert R.; Bartsch, Richard A.
Tetrahedron, 2004 , vol. 60, # 9 p. 2035 - 2041
反应条件
sodium iodide in acetone
30 h; Heating;
参考文献
Curran, Dennis P.; Bosch, Eric; Kaplan, Jere; Newcomb, Martin
Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1826 - 1831
反应条件
boric acid trimethyl ester; zinc in tetrahydrofuran
24 h; Ambient temperature;
参考文献
Eilbracht, Peter; Acker, Michael; Rosenstock, Bernd
Chemische Berichte, 1989 , vol. 122, p. 151 - 158
反应条件
(i) , (ii) (saponification), (iii) (decarboxylation); Multistep reaction;
参考文献
Marxmeier,H.; Pfeil,E.
Chemische Berichte, 1964 , vol. 97, p. 815 - 826
反应条件
mercury dichloride; zinc in diethyl ether; benzene
参考文献
Lapkin,I.I.; Fotin,V.V.
Journal of Organic Chemistry USSR (English Translation), 1975 , vol. 11, p. 2360 - 2362
Zhurnal Organicheskoi Khimii, 1975 , vol. 11, # 11 p. 2319 - 2322
反应条件
zinc
zersetzt mit Wasser;
参考文献
Blaise
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1901 , vol. 132, p. 479
