4-溴-2,6-二甲基苯基乙酸酯合成路线 （共 3 条）
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane
T=23°C; 1 h;
参考文献
PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2007/1249 A1, 2007 ;
Location in patent: Page/Page column 38-39 ;
反应条件
gold(III) chloride in 1,2-dichloro-ethane
T=110°C; 6 h; regioselective reaction;
参考文献
Qiu, Di; Zheng, Zhitong; Mo, Fanyang; Xiao, Qing; Tian, Yu; Zhang, Yan; Wang, Jianbo
Organic Letters, 2011 , vol. 13, # 19 p. 4988 - 4991
反应条件
(i) Br2, (ii) /BRN= 385737/; Multistep reaction;
参考文献
Wieder,W. et al.
Justus Liebigs Annalen der Chemie, 1976 , p. 924 - 945
